Our laboratory investigates the neural mechanisms underlying decision making, motivation and reward processing in humans, using concepts from cognitive neuroscience, psychology and behavioral economics. We use experimental tools such as model-based functional Magnetic Resonance Imaging, intracranial electrophysiological recordings and pharmacological manipulations to understand the computational processes involved when making a choice. Our goals are to understand the functional organization of the prefrontal cortex in humans, the various functions that the reward dopaminergic system exerts on cognition and motivation and the neural mechanisms underlying dysfunctions of these two systems in patients with neurological or psychiatric illnesses (Parkinson’s disease, patients with focal prefrontal cortex lesions, schizophrenia and pathological gambling). In parallel, we are also studying how individual variations in hormones and genes influence reward processing and decision-making.

Open positions

Applications are invited for a postdoctoral position to study neuroeconomics, decision making, motivation and reward processing using fMRI in healthy subjects and patients with neurological disorders.

Apply here >>


August 20th
A team at the Laboratoire biologie fonctionnelle et adaptative (CNRS/Université Paris Diderot) investigated the relative role of energy needs and "pleasure" of eating in food intake. The researchers studied a group of neurons in mice. They observed…
August 5th
Scientists have just identified in the mouse, and then confirmed in humans, a new factor that regulates addiction. Glutamate, a neurotransmitter, contributes to regulating dopamine release in the nucleus accumbens, one of the cerebral structures of the re…
August 5th
Our bodies have ten times more microbes than human cells. This set of bacteria is called microbiota. In some instances, bacteria known as pathogens can cause infectious diseases. However, these micro-organisms can also protect us from certain diseases. Re…
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