gbfr

Our laboratory investigates the neural mechanisms underlying decision making, motivation and reward processing in humans, using concepts from cognitive neuroscience, psychology and behavioral economics. We use experimental tools such as model-based functional Magnetic Resonance Imaging, intracranial electrophysiological recordings and pharmacological manipulations to understand the computational processes involved when making a choice. Our goals are to understand the functional organization of the prefrontal cortex in humans, the various functions that the reward dopaminergic system exerts on cognition and motivation and the neural mechanisms underlying dysfunctions of these two systems in patients with neurological or psychiatric illnesses (Parkinson’s disease, patients with focal prefrontal cortex lesions, schizophrenia and pathological gambling). In parallel, we are also studying how individual variations in hormones and genes influence reward processing and decision-making.

Open positions

Applications are invited for a postdoctoral position to study neuroeconomics, decision making, motivation and reward processing using fMRI in healthy subjects and patients with neurological disorders.

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CNRS News

November 20th
• The aim is to accelerate the development of new formulations of drugs based on self-assembly of peptides • Five-year public-private research partnership, built on 15 years of collaboration
November 14th
The European Medicines Agency (EMA) has granted "orphan designation" to BMS 204352 , a molecule developed by the CNRS to treat Fragile X Syndrome, a rare genetic disease for which there exists no treatment. Protocol assistance will therefore be provided b…
November 5th
The ability to build up knowledge over generations, called cumulative culture, has given mankind language and technology. While it was thought to be limited to humans until now, researchers from the Laboratoire de psychologie cognitive (CNRS/AMU), working…
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