Our laboratory investigates the neural mechanisms underlying decision making, motivation and reward processing in humans, using concepts from cognitive neuroscience, psychology and behavioral economics. We use experimental tools such as model-based functional Magnetic Resonance Imaging, intracranial electrophysiological recordings and pharmacological manipulations to understand the computational processes involved when making a choice. Our goals are to understand the functional organization of the prefrontal cortex in humans, the various functions that the reward dopaminergic system exerts on cognition and motivation and the neural mechanisms underlying dysfunctions of these two systems in patients with neurological or psychiatric illnesses (Parkinson’s disease, patients with focal prefrontal cortex lesions, schizophrenia and pathological gambling). In parallel, we are also studying how individual variations in hormones and genes influence reward processing and decision-making.

Open positions

Applications are invited for a postdoctoral position to study neuroeconomics, decision making, motivation and reward processing using fMRI in healthy subjects and patients with neurological disorders.

Apply here >>


July 11th
A new ultrasound imaging technique has provided the first ever visualization of activity in the piriform cortex of rats during odor perception. This deep-seated brain structure plays an important role in olfaction, and was inaccessible to functional imag…
June 30th
Through an innovative approach using a large psychometric and brain imaging database, researchers in the Groupe d'Imagerie Neurofonctionnelle (CNRS/CEA/Université de Bordeaux) have demonstrated that the location of language areas in the brain is in…
June 13th
For the first time, CNRS researchers and the Université de Bordeaux have produced and observed anxiety-like behavior in crayfish, which disappears when a dose of anxiolytic is injected. This work, published in on June 13, 2014, shows that the neur…
- Copyright 2013 ISC-CNRS Created by Francesco De Fina